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It has been proved that glioma cell lines, such as U87, LN18, U251, and SF767 are sensitive to metformin treatment (Table 2)
This NP is a selective epithelium transport and drug internalization, with low side effects due to controlling the release profile

Together, these opposing effects make GDF15 a promising mechanistic target for understanding and modulating aging-related diseases

Anatomical, Physiological, and Functional Diversity of Adipose Tissue
