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Description
6PR and Supplementary Fig

Its cytotoxic mode of action is mediated by its interaction with DNA to form DNA adducts, primarily intrastrand crosslink adducts, which activate several signal transduction pathways, including those involving ATR, p53, p73, and MAPK, and culminate in the activation of apoptosis

doi:10.1016/j.tips.2019.11.001 46

S100B: S100 calcium-binding protein B