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TMAO and the inflammasome NLRP3 The activation of the NLRP3 inflammasome is a critical mediator of TMAO-induced pro-inflammatory effects
Romigi et al
The New England Journal of Medicine, 341, 491-497
The primary structure of Ozz consists of two NHR (Neuralized Homology Repeat) domains, which are responsible for substrate recognition, and a C-terminal SOCS box that mediates interaction with the Elongin B/C complex 30,31
