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In biological systems, HOCl is formed during the process of phagocytosis catalyzed by myeloperoxidase-mediated peroxidation of chloride anions (Cl ) using hydrogen peroxide (Hadjigogos 2003)

The fairly nonspecific findings described include vacuolar degeneration of the basement membrane, necrotic keratinocytes, and superficial vascular ectasia.35 A mixed inflammatory infiltrate, dermal sclerosis, and a psoriasiform pattern of dermatitis are also common.36 Pathophysiologic observations described in the context of recall phenomenon have included vascular injury in the irradiated zone31 and cellular reduction or changes in the basement membrane of the epidermis.37 Currently the most widely accepted theory holds that recall phenomenon is a hypersensitivity drug reaction35 similar to a fixed drug eruption

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In a comprehensive study involving 90 patients with CRC, immunohistochemical analysis revealed a substantially higher expression of ASCT2 in CRC tissues than that in normal mucosal tissues