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T-cells become activated when they are exposed to antigen (Steinman, 1991

Surface plasmon resonance The affinities of TCEs for all cognate antigens (p/p*MHCs) exploited in this study were determined by using a Biacore 1 K+ instrument (Cytiva, Insight Control v5.0.18.22102) loaded with a Series S high-affinity streptavidin (SA) sensor chip (Cytiva, BR100531) and 6 flow cells

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The absence of a significant effect with CBBBP alone suggests that the CBBBP construct may require the DSIP component to engage with the relevant neural pathways effectively