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The best treatment is prevention, treating causes, correcting calcium and vitamin D, exercise program Medical treatment includes hormonal replacement, bisphosphonates, calcitonin, raloxifene, teriparatide Nonsurgical treatment includes bedrest, cast/brace, analgesia If conservative treatment fails, surgeryminimally invasive (vertebroplasty or kyphoplasty) or invasive, open approach to the spine is indicated

siRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury

Arch Gen Psychiat 47: 11701172

Soares et al., 2019)
