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2014 Apr;27(3):331-6

Transduce and amplify: Often, a signal needs to be transformed so that it can be used in other ways

Furthermore, it was reported that TAU significantly suppresses the cell proliferation induced by the platelet-derived growth factor (PDGF)-BB via the protein tyrosine phosphatase (PTPase)-mediated suppression of the PDGF- receptor phosphorylation and by decreasing the activation of its downstream signaling molecules in VSMCs 37

10.1016/S0028-3908(01)00171-X Neuropharmacology 31 HoT
