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G6PD deficiency: the genotype-phenotype association

Phosphofructokinase-1 subunit composition and activity in the skeletal muscle, liver, and brain of dogs

Although a decrease in circulating and skeletal muscle IGF-1 has been reported in various chronic conditions, including cancer, congestive heart failure, chronic kidney disease, and COPD, and aging [5,163] (Figure 2), more studies are required to determine whether IGF-1 administration could be a therapeutic approach to treat muscle atrophy in these patients (discussed below)

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