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[44] Jules Hoffmann and colleagues had earlier shown that the Drosophila Toll protein, originally known for its role in embryogenesis, was essential for the antimicrobial peptide response to fungal infection

Animal experiments revealed that the expression of ferroportin, a transmembrane protein that drives iron efflux outside of the cell, is accompanied by increased levels of endothelin-1, a potent endogenous vasoconstrictor

Uncoupling insulin signalling by serine/threonine phosphorylation: A molecular basis for insulin resistance

Due to its potency and ability to reactivate other antioxidants, it is known as the king of all antioxidants