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[DOI] [PubMed] [Google Scholar] 555.Franci G., Sarno F., Nebbioso A., Altucci L
Ice-crystal formation during each freeze-thaw cycle inflicts mechanical damage on peptide chains, and pre-splitting eliminates the cumulative loss that comes from thawing one vial multiple times

An overview of in vivo toxicological profile of thymoquinone
