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This effect is primarily attributed to methylxanthines, such as theobromine, which induces LES relaxation through a mechanism similar to caffeine (Reference Fredholm190)
Effects of milk yield, feed composition, and feed contamination with aflatoxin B1 on the aflatoxin M1 concentration in dairy cows milk investigated using monte carlo simulation modelling

Kidneys have many functions, they principally act to remove nitrogenous waste products from the blood stream, maintain essential nutrients e.g

To date, pharmacotherapy remains the mainstay for improving the quality of life in PD patients
