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Related studies have confirmed that adeno-associated viruses that allow the exclusive expression of Jumonji domain-containing protein D3 (JMJD3) in macrophages can be generated under the macrophage-specific CD68 promoter in streptozotocin-induced diabetic male mice, thereby transducing testicular macrophages back to M2-like phenotype to exhibit an anti-inflammatory state to alleviate the negative effects of diabetes on sperm motility, serum and testicular testosterone levels (Zhu et al

13 Researchers found improvements in sural nerve conduction velocity and amplitude, and improved neuropathic pain symptoms that were similar in both treatment groups and were significant when compared with placebo

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