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As the most frequently reported mutation site, R246 C in the C-loop forms multiple hydrogen bonds with residues in L5 (Fig

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While specific studies on the arginate form in neural tissue are limited, the shared mechanism of action suggests similar potential

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Tirzepatide occupies the middle ground: broader than classical GLP-1 analogues, but more selective than triple agonists

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[9] [10] [11] [12] Neurologically, magnesium acts to block the release of acetylcholine at the neuromuscular junction, thereby inhibiting peripheral neuromuscular transmission

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