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Depending on their availability, certain metabolites can modify gene expression, protein function, and the epigenetic profile of the cell, ensuring a rapid adaptive response to changes in energy demand [1]

Towards the end of the secretory phase, prior to the onset of menses, the endometrium has differentiated into three zones: the deepest layer remains the unchanged basalis layer, the middle layer is the stratum spongiosum, or loose edematous stroma containing tightly coiled spiral vessels and dilated glands, and the most superficial layer is the more stromally dense stratum compactum (Owusu-Akyaw et al., 2019)

This makes it good for injury modeling, recovery timing studies, and tissue resilience testing

After 18 hours, luminol and HPI were added to the wells, both to 250 M final concentration