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However, since the key point in this group of patients is to remove weight, this patient group is also satisfied with the result

doi: 10.1111/j.1530-0277.1993.tb00812.x

Since tumor cells residing in regions of hypoxia and/or acidosis (and hence expressing CA IX) are inherently associated with therapy resistance, it is conceivable that chemotherapy/radiotherapy will leave these cells alive and permit their proliferation in metastatic lesions
