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Domnguez A, Surez-Merino B, Goi-de-Cerio F

Conversely, tumor cells that upregulate GPX4 or maintain high GSH pools can evade ferroptosis, supporting proliferation and resistance to oxidative therapies (42, 43)

CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1

Increasing CSL concentration to 5% and 10% (v/v) significantly increased glutathione production concentration, resulting in 2.1- and 2.4-fold improvements, respectively, compared to the YCK50D medium (Fig
