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Description
Various monoclonal antibodies have been developed to block c-Met/HGF signaling pathways, some of which competitively bind to c-Met, and the others are served as traps for c-Met, preventing ligand attachment and dimerization of c-Met [168]
Thus, this raises concerns about the long-term safety of PLGA-based delivery systems for PD 97,107
These include direct hepatotoxicity from alcohol metabolites like acetaldehyde and reactive oxygen species, leading to cellular damage [12]

Beckman J