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[DOI] [PubMed] [Google Scholar] 37.Tseng KF, et al

Many research efforts have been conducted to delay the introduction of levodopa in patients, which has eventually led to the development of dopamine agonists as monotherapy, with a theory stating that the administration of dopamine agonists can delay the development of motor complications if administered before levodopa [20]

This happens when you dont equalize the pressure first

[DOI] [PMC free article] [PubMed] [Google Scholar] 21.Cenini G., Voos W