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When patients learn (sometimes the hard way) that using opioids will not give the high they are looking for and can cause 10/10 withdrawal sickness, its clearly not worth the relapse
doi:10.7554/eLife.13185
10.1200/JCO.2000.18.24.4086 52 ElhusseinyS
10.1074/jbc.c100512200 5 AlbistonA
