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Trends Endocrinol Metab 15, 5559, doi: 10.1016/j.tem.2003.12.002 (2004)
Matta SF, Gieselman LA, Mancini RS

At iLIFE Anti-Aging Center, patients benefit from advanced regenerative anti-aging medicine designed to enhance vitality, physical performance, and overall health

For example, the prodrug and cancer chemotherapeutic agent irinotecan is a camptothecin analog that is bioactivated by plasma and intracellular carboxylesterases to SN-38 ( Figure 65 ), a potent inhibitor of topoisomerase 1