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In a 72-week, double-blind phase 2 trial in patients with biopsy-confirmed NASH (legacy term) and fibrosis stage F1F3, once-daily subcutaneous semaglutide produced dose-dependent NASH resolution: 59% at the 0.4 mg dose versus 17% with placebo (a statistically significant difference)
The studies were approved by the University of Pittsburgh Institutional Review Board (IMSA, PRO15050456
Determination of Microscopic Acid-Base Parameters from NMR-pH Titrations
