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Description
These observations support the notion that AD is a degenerative metabolic disease in which the impairment of glucose metabolism, mediated by reduced brain glucose uptake and lowered insulin responsiveness, is closely associated with increased OS and inflammation (392)
In addition, TRPM5 is activated by intracellular Ca 2+ with greater sensitivity than TRPM4 (Ruan et al., 2021
[DOI] [PubMed] [Google Scholar] Schaeffer, E
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