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The decrease of neurotrophins, in serum and in CNS (33) has been associated with the formation of A and pTau plaques (3436)
In animal models, C2 supplementation promoted neuroplasticity, synthesis of neurotrophic factors, modulation of glutamatergic dysfunction, reversal of neuronal atrophy in regions like the hippocampus and amygdala, and improvement in depression-like behavioral symptoms [20, 30, 57, 58]
10.1016/j.scitotenv.2018.06.084 [DOI] [PubMed] [Google Scholar] Wu X., Chen L., Zeb F., Huang Y., An J., Ren J
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