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The only thing that changes is the concentration, which you set during reconstitution

A researcher reconstitutes with 1mL of water (5mg/mL concentration) but follows a dosage chart designed for 2mL reconstitution (2.5mg/mL)

Future studies will be focused on optimizing the MQ-scaffold lead series to generate more potent NNMT inhibitors with significantly improved drug-like ADME profile