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Deficiency in vitamin B6 is commonly linked to malnutrition, alcoholism, malabsorption syndromes, or as an adverse effect of certain medications, such as cyclosporine, hydralazine, cycloserine, penicillamine, isoniazid, levodopa, phenelzine and chemotherapy treatments (, , , )

Note: No control group (vegetarians without supplements) or total placebo group, for ethical reasons (we know that not giving B12 to someone with a deficiency exposes them to serious problems

Absorption rates for oral supplements range from 10% to 60%, depending on the nutrient and individual factors [8] [3]

Artificial extracellular matrices composed of collagen I and sulfated hyaluronan with adsorbed transforming growth factor 1 promote collagen synthesis of human mesenchymal stromal cells