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Unnecessary supplementation is not recommended, as it provides no additional benefit in individuals with adequate B12 status

16 BubenekS.NastaseA.NiculescuA

A well-functioning homocysteine pathway is important for numerous aspects of health including normal detoxification, immune function, joint and cartilage health, cardiovascular health, and brain health

In a trial of patients with T2DM and BMI 27 kg/m2 or more receiving semaglutide injection for weight management, retinal disorders were reported by 6.9% of patients treated with semaglutide 2.4 mg/week, 6.2% of patients treated with semaglutide 1 mg/week, and 4.2% of patients treated with placebo