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Description
MTH1 inhibitor TH1579 induces oxidative DNA damage and mitotic arrest in acute myeloid leukemia
T., Horng, J
this leads to reduced neuronal glucose uptake and impairment of aerobic glycolysis and the TCA cycle and results in symptoms of insulin resistance and a low rate of glucose utilization in the brains of AD patients (De Leon et al., 1983
Plasma levels higher than this range are classified as mild/moderate, intermediate, or severe hyperhomocysteinemia2: mild/moderate: 15 to 30 mol/L
