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Gastroenterology 134 , 16551669 (2008)

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While such a combined approach might compromise GLO-1s detoxification function the overall effect could ultimately be detrimental to cancer development

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Thom R, Dixon DP, Edwards R, Cole DJ, Lapthorn A: The structure of a zeta class glutathione S -transferase from Arabidopsis thaliana : characterization of a GST with novel active site architecture and a putative role in tyrosine catabolism

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The pathway is quite efficient: for example, it maintains the ratio NADPH/NADP+ at ~100 in the liver of a normal healthy individual

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