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Biochem Pharmacol 43(8):16571669 Zhong B, Yu J, Hou Y, Ai N, Ge W, Lu JJ et al (2021) A novel strategy for glioblastoma treatment by induction of noptosis, an NQO1-dependent necrosis
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It has been found that in many other organs and tissues, such as the dorsal root ganglion (GDR), the GPx is the first enzyme that is activated under high levels of EROS, indicating the importance of this enzyme as a first line of defense against stress oxidative [96, 97]

They discovered a ligand-induced protein tethering (LIPT) molecular glue mechanism revealing new PPIs, altered protein localization, and disrupted cancer metabolism
