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Results Here, in normal rats, after tail amputation (spontaneous bleeding for 20 minutes, fall in platelet count without any failure of coagulation parameters) the previous effects of BPC 157 (reduced bleeding, no thrombocytopenia) [15] were confronted with that of L-arginine (prolonged bleeding without thrombocytopenia) and L-NAME (reduced bleeding, thrombocytopenia present), given alone and/or combined

BPC 157 co-administration restated a beneficial effect in the NO-system immobilization (the L-NAME+L-arginine+BPC 157 rats), and BPC 157 overwhelmed the effect of L-arginine as well as the effect of L-NAME and counteracted NO-system immobilization