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BDNF regulates synaptic plasticity through interactions with the tropomyosin-related kinase B (TrkB) receptor and induction of several signaling cascades that are involved in the regulation of synaptic plasticity and cAMP-responsive element-binding protein (CREB)-dependent gene expression 13
Managing side effects by dose tier At 1mg, most researchers need no specific management

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1996;150(Suppl):S259-265