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Description
& Leeb, T

Species: Human (Homo sapiens)

Time-dependent cytotoxicity was most evident at 580 M as the cell viability was greatest at 24 h, followed by 48 h and the least at 72 h

Human liver P450s 3A4, 2C9, 2D6, 2C19, 1A2, and 2B6 are responsible for about 75% of all clinically relevant phase I drug metabolism ( Figure 44 ), and thus for about 60% of all physiologic drug biotransformation and elimination
