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p300, CREB binding protein (CBP), and steroid receptor coactivator-1 (SRC-1) act as cofactors to form the HIF-1 transcription complex [47]

This amino acid is also used as the main oxidative fuel to replenish intermediates of the tricarboxylic acid cycle in rapidly dividing cells [1], such as enterocytes and colonocytes [6], fibroblasts, and immune cells such as lymphocytes [7, 8], macrophages, and neutrophils [9,10,11,12]

doi: 10.1002/jbt.20042

Heme oxygenase-1 modulates ferroptosis by fine-tuning levels of intracellular iron and reactive oxygen species of macrophages in response to Bacillus Calmette-Guerin infection