glutathione system biochemistry Mode of action of Amino acid Precursors (GAP) and functions Team:UNSW Australia/Model/Glutathione System

Lipid peroxidation plays a pivotal role in the pathogenesis of numerous diseases, including neurodegenerative disorders (e.g., Alzheimer's disease), cardiovascular diseases, and metabolic syndromes [54, 55]

Lipid metabolic reprogramming in tumor microenvironment: from mechanisms to therapeutics

Although Compounds 1.65 and 1.71 lost efficacy in a major detoxification process of GSH by being unable to interact with the GST enzyme, this did not indicate a loss for all detoxification pathways

On this basis and considering that brain organoids are 3D cytoarchitectures resembling the embryonic human brain, many researchers and companies are developing protocols and pipelines for the generation, maintenance and analysis of brain organoids to model neurodevelopmental diseases (Lee et al., 2017