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S1a) GSH concentrations changed by mito GCL expression

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Multidrug Resistance-associated Protein 1 (MRP1) and MRP2, of the ABC (ATP-Binding Cassette)-type subfamily C transporters, transport oxidized glutathione and glutathione S-conjugates when expressed in yeast 58,59 and might be involved in their transport from the cytosol into the vacuole in plants