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Brayan RoulierBrayan RoulierDpartement de Pharmacochimie Molculaire (DPM), UMR 5063, Universit Grenoble Alpes, 38041 Grenoble, FranceMore by Brayan Roulier Basile PrsBasile PrsDpartement de Pharmacochimie Molculaire (DPM), UMR 5063, Universit Grenoble Alpes, 38041 Grenoble, FranceMore by Basile Prs Romain Haudecoeur * Romain HaudecoeurDpartement de Pharmacochimie Molculaire (DPM), UMR 5063, Universit Grenoble Alpes, 38041 Grenoble, France * E-mail: [email protected]More by Romain Haudecoeur Abstract Human tyrosinase ( hs TYR) is the key enzyme ensuring the conversion of l-tyrosine to dopaquinone, thereby initiating melanin synthesis, i.e., melanogenesis