increased glutathione levels gliomas autophagy Frontiers Methionine cycle inhibition disrupts antioxidant
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Mechanistically, the reductive stress observed in R120G mutant mice was attributed to activation of the nuclear factor (erythroid-derived 2)-like 2 (NRF-2) signaling pathway, which transcriptionally upregulated the mRNA or/and protein expression of key antioxidant enzymes ( e.g

Inhibition of NBT is proportional to the amount of SOD (Fig

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