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Within the mitochondrial matrix, Mn-dependent superoxide dismutase (MnSOD) converts O 2 into hydrogen peroxide
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The IL-1 beta-converting enzyme (caspase-1) inhibits apoptosis of inflammatory neutrophils through activation of IL-1 beta
In this context, hormones such as melatonin and cortisol, as well as circulating elements in blood or lymphatic fluid, including immune cells, neuropeptides, and neurotransmitters like dopamine, noradrenaline, and serotonin, are key components of the circadian system (Linsell et al., 1985
