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Data were expressed as the percentage of the positive-stained region to the total area of cardiomyocyte area, and averaged from six random fields in each slide

10.1016/j.ijbiomac.2022.07.176 43

D.PlumbJ.NeedsP

The instability of hydrazone linkers is presumably caused by their slow hydrolysis under physiological conditions that leads to a progressive release of the drug in circulation and enhanced risk of systemic toxicity