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Description
Human RTKs containing 20 subfamilies including epidermal growth factor receptor (EGFR), vascular endothelial growth factor receptor (VEGFR), platelet-derived growth factor receptors (PDGF-R), fibroblast growth factor receptors (FGFR), insulin-like growth factor 1 receptor (IGF-1R), and hepatocyte growth factor receptor (c-Met or HGFR)

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Mouse studies have revealed its potentially higher permeability and lower efflux rate compared with the other type 1b drug treatments on the market, fostering a hopeful outlook in future treatment options for METEx14 patients [104]

However, as amylin potency on this receptor is relatively small, very high plasma concentrations of amylin are needed to cause an effect [24]
