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Meanwhile, insufficient extracellular methionine supply in the tumor microenvironment augments PD-1 expression through decreasing the H3K79me2 level in CD4 + T cells (123)

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thus, the phenotype is manifest fully in males whereas female heterozygotes display varying degrees of G6PD deficiency, due to alternate X-chromosome inactivation 3,4

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Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram-negative bacterial outer membrane

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