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Introduction First identified by Albert Claude in 1945 1 , the endoplasmic reticulum (ER) was later defined by George Palade through electron microscopy as a highly specialized membrane-bound organelle essential for the synthesis, folding, and maturation of secretory and membrane proteins 2

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In contrast to these findings, GPX4 inhibition did not impact cell death during human erythroblast differentiation, as recently published by Ouled-Haddou et al

