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(166) revealed that the segmentation motor pattern emerges when the amplitude of the dominant pacemaker in the gut, in this case the mechanical slow wave generated by ICCs associated with the myenteric plexus, is modulated by the phase of an induced lower-frequency rhythmic transient depolarization, generated by ICC associated with the deep muscular plexus

These proteins exert numerous functions such as serving as intracellular Ca 2+ sensors, transduction of Ca 2+ signaling, response to extracellular stimuli, energy metabolism, and regulating cell proliferation and apoptosis

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Angiogenesis, the formation of new blood vessels, represents the third critical mechanism