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Prior studies have shown that ROS levels influence IL-10 production, with Complex I-derived ROS suppression enhancing IL-10 production 32,33 , but in contrast, Complex III-derived ROS is required for IL-10 production 2

10.1152/physiol.00006.2015 [DOI] [PubMed] [Google Scholar] Baird L, Yamamoto M (2020) The molecular mechanisms regulating the KEAP1-NRF2 pathway

NRF2 then binds to antioxidant response elements (ARE) [131], inducing the expression of various antioxidant genes such as SOD, CAT, and HO-1 [132, 133]

doi: 10.1002/hep.23054 145 Ostrand-RosenbergSSinhaPBeuryDWClementsVK
