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Digestive : Pancreatitis, jaundice (intrahepatic cholestatic jaundice), diarrhea, vomiting, sialadenitis, cramping, constipation, gastric irritation, nausea, anorexia

Sources The Effectiveness of Cobalamin (B12) Treatment for Autism Spectrum Disorder: A Systematic Review and Meta-Analysis Journal of Personalized Medicine (2021) Vit B12 supplement of 500 g/d for eight weeks does not normalize urinary methyl-malonic acid or other biomarkers of vitamin B12 status in elderly people J Nutr

While its best-known role is in erythropoiesis (red blood cell formation), its also involved in: DNA synthesis Regeneration of bone marrow, GI lining, and respiratory tract lining Nervous system development and maintenance (11) Prevention of anemia Although a B12 deficiency isnt as common as vitamin D or even folate, it still happens

Some pharmacists recommend compounding, the process of creating customized drugs
