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The transcription of Sele in the low-density lipoprotein pathway was upregulated by 4.00 folds, while Wisp in the Wnt pathway was upregulated by 2.21 folds
AF, WA, and HQ contributed to writing the original draft
4.3 The vicious cycle of metabolic deficits and immune activation Mitochondrial dysfunction may result in overproduction of ROS and the release of mtDNA, both of which serve as DAMPs, activating the NLRP3 inflammasome in both peripheral and central immune systems, thereby promoting the release of pro-inflammatory cytokines, such as IL-1 and IL-18 (168170)
