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Novel pH-dependent regulation of human cytosolic sialidase 2 (NEU2) activities by siastatin B and structural prediction of NEU2/siastatin B complex

Moreover, our results revealed the enhancement pattern in antioxidant contents

Additionally, alignment to the central helical Z -axis and a simple morph of the global basal and activated models show that the large conformational change is possible in the filament with fewer clashes when the CD moves in concert with the RDs (Supplementary Fig

1 Introduction Mitochondria, as quintessential organelles in eukaryotic cells, serve dual roles as cellular energy suppliers and key regulators of calcium homeostasis, oxidative stress responses, and apoptotic signaling pathways (Kamer and Mootha, 2015