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A 20-year follow-up study on chronic respiratory effects of exposure to cotton dust

But for researchers who find the GI effects of full weekly doses difficult to manage, the trade-off is often worth it

In this Review, we focus on advances in our understanding of inhibition of the HGF/c-MET pathway in patients with gastro-intestinal cancers, the prominent challenges facing the clinical translation and implementation of agents targeting HGF/c-MET, and discuss the various efforts, and associated obstacles to the discovery and validation of biomarkers that will enable patient stratification in this context

This approach ensures high local concentrations where healing is needed most