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One mechanism of this effect is that THC arrests the cells at the G 2 -M cell cycle checkpoint via downregulation of the cyclin-dependent kinase 1 (Cdc2), as suggested by the reduced sensitivity of Cdc2-overexpressing cells to THC (144)

The second trial, conducted at Peking University Third Hospital (Ethical code: D2020188), was a Phase I clinical triala randomized, double-blind, controlled study aimed at assessing the safety and preliminary efficacy of DPSC therapy at varying dose concentrations, carried out from July 31, 2021, to December 24, 2022

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229,230,231,232 Therefore, GM-CSF can be a potential factor in designing new drugs against asthma