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So far, can be used for obesity, type 2 diabetes, cardiovascular risk, and obstructive sleep apnea
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In addition to SAM depletion, even inactive NNMT can interact with betaine-homocysteine methyltransferase (BHMT), methionine adenosyltransferase (MAT), and adenosylhomocysteinase (AHCY) to regulate methyl donor balance (96, 97)
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